Meningitis due to a combined infection with Cryptococcus neoformans and Streptococcus pneumoniae in an AIDS patient.

We report on a case of dual infection with Cryptococcus neoformans and Streptococcus pneumoniae in the cerebrospinal fluid of a patient with AIDS. To our knowledge this represents the first case to be reported in the English literature. In immunocompromised patients the importance of performing both the Gram- and India-ink stain and cryptococcal antigen test on CSF specimens with completely normal biochemical and cellular parameters is emphasized.