[A case of Guillain-Barré syndrome with primary symptoms of radicular pain in whom intravenous methylprednisolone therapy was effective].

A 62-year-old woman was admitted to our hospital with severe pain in all extremities and difficulty in moving. Neurological findings included sensory disturbances with severe pain, weakness, and areflexia in all extremities, with positive Spurling and Lasègue signs. Cerebrospinal fluid analysis revealed protein-cell dissociation. A nerve conduction study revealed the appearance of A-waves and loss of F-waves. Lumbar magnetic resonance imaging revealed gadolinium enhancement in the cauda equina. Therefore, the patient was diagnosed with Guillain-Barré syndrome (GBS) with severe radicular pain. Initially, we started and repeated intravenous immunoglobulin with half-intravenous methylprednisolone pulse therapy (IVMP) and added several types of painkillers, such as acetaminophen, pregabalin, and duloxeline; however, the symptoms, especially severe pain, did not improve significantly. We administered IVMP, and severe radicular pain drastically improved on the first day of IVMP. Here, we describe a case of GBS with primary symptoms of radicular pain, in whom IVMP was effective for radicular pain.