Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2013
Percutaneous endoscopic gastrostomy site metastasis from head and neck squamous cell carcinoma: case series and literature review.
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Huang Andrew T, Georgolios Alexandros, Espino Sasa, Kaplan Brian, Neifeld James, Reiter Evan R
Аннотация
OBJECTIVES: To present our experience with head and neck squamous cell carcinoma (HNSCC) seeding of percutaneous endoscopic gastrostomy (PEG) sites and to review all reported cases to identify risk factors and develop strategies for complication avoidance.
MATERIALS AND METHODS: The records of 4 patients with PEG site metastasis from HNSCC were identified from the authors' institution. Thirty-eight further cases were reviewed following a PubMed search and evaluation of references in pertinent articles.
RESULTS: Review of 42 cases revealed the average time from PEG to diagnosis of metastatic disease to be 8 months. Average time to death from detection of PEG disease was 5.9 months. One-year survival following PEG metastasis was 35.5% with an overall mortality of 87.1%.
CONCLUSION: PEG site metastatic disease portends a poor prognosis. Early detection and aggressive therapy may provide a chance of cure. Changes in PEG technique or in timing of adjunctive therapies are possible avenues in further research to prevent this complication.
MATERIALS AND METHODS: The records of 4 patients with PEG site metastasis from HNSCC were identified from the authors' institution. Thirty-eight further cases were reviewed following a PubMed search and evaluation of references in pertinent articles.
RESULTS: Review of 42 cases revealed the average time from PEG to diagnosis of metastatic disease to be 8 months. Average time to death from detection of PEG disease was 5.9 months. One-year survival following PEG metastasis was 35.5% with an overall mortality of 87.1%.
CONCLUSION: PEG site metastatic disease portends a poor prognosis. Early detection and aggressive therapy may provide a chance of cure. Changes in PEG technique or in timing of adjunctive therapies are possible avenues in further research to prevent this complication.
Предметные рубрики MeSH
Abdominal WallAgedCarcinoma, Squamous CellCombined Modality TherapyFatal OutcomeGastrostomyHead and Neck NeoplasmsHumansHypopharyngeal NeoplasmsLaryngeal NeoplasmsMaleMiddle AgedNeck DissectionNeoplasm Recurrence, LocalNeoplasm SeedingPrognosisPyriform SinusRadiotherapy DosageRetrospective StudiesRisk FactorsSquamous Cell Carcinoma of Head and NeckStomach NeoplasmsTongue Neoplasms