Journal of occupational and environmental medicine · 2025
Benzene and Pituitary-Thyroid Axis in Workers Exposed to Urban Pollution.
СтатьяНазвание и аннотация: Перевод в очереди
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Giammichele Grazia, Montuori Lucio, Sacco Carmina, Corsale Silvia, Massimi Roberto, Ciccolini Flavio, Suppi Anastasia, Tomei Francesco, Ricci Lidia, Marchione Stefania, Tomei Gianfranco
Аннотация
OBJECTIVE: The aim of this study is to verify if outdoor workers' exposure to low dose of benzene in urban air may affect thyroid hormone levels.
METHODS: The study was conducted on a total sample of 334 subjects. Benzene's environmental monitoring has been performed through personal dosimeters, whereas, for the biological monitoring, we have measured the concentration of blood benzene, trans,trans-muconic acid (t,t-MA) urinary, and S-phenylmercapturic acid (S-PMA) urinary on thyroid hormones. The statistical analysis was performed.
RESULTS: Statistic test shows that there is a negative correlation between blood benzene levels, t,t-MA urinary, FT3, and FT4; there is a positive correlation between blood benzene, t,t-MA urinary, and TSH.
CONCLUSIONS: Occupational exposure to low dose of benzene in urban pollution can affect thyroid hormone levels in occupationally exposed workers.
METHODS: The study was conducted on a total sample of 334 subjects. Benzene's environmental monitoring has been performed through personal dosimeters, whereas, for the biological monitoring, we have measured the concentration of blood benzene, trans,trans-muconic acid (t,t-MA) urinary, and S-phenylmercapturic acid (S-PMA) urinary on thyroid hormones. The statistical analysis was performed.
RESULTS: Statistic test shows that there is a negative correlation between blood benzene levels, t,t-MA urinary, FT3, and FT4; there is a positive correlation between blood benzene, t,t-MA urinary, and TSH.
CONCLUSIONS: Occupational exposure to low dose of benzene in urban pollution can affect thyroid hormone levels in occupationally exposed workers.