A MODEL FOR PROGNOSIS OF ACUTE LEFT VENTRICULAR FAILURE IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND TYPE 2 DIABETES MELLITUS CONSIDERING TENASCIN C CONTENT.

The role of tenascin C in patients with acute myocardial infarction and type 2 diabetes mellitus still remains disputable today. The purpose of the study is to elaborate a model for the prediction of left ventricular failure in patients with acute myocardial infarction and type 2 diabetes taking into account the level of tenascin C, as well as to evaluate the prognostic value of this indicator in the development of acute myocardial infarction. The study showed that over time the content of tenascin C decreased on the 10th-12th day in patients with acute myocardial infarction and type 2 diabetes mellitus compared to patients with acute myocardial infarction without type 2 diabetes. The results demonstrated predictive properties of tenascin C in the development of acute myocardial infarction in patients with type 2 diabetes. The study allowed the authors to elaborate a model for the prognosis of acute left ventricular failure, taking into account the level of tenascin C. Combination of tenascin C dynamics and frequency of respiratory movements increased prognostic properties of the model, particularly its sensitivity (84%) and specificity (83%). Thus, the study proved the expediency of the model based on tenascin C indices for prognosis of acute left ventricular failure in patients with acute myocardial infarction and type 2 diabetes mellitus.