[Reactivity of the neuroglia in guinea pigs sensitized with Mycobacteria tuberculosis].

The changes in the glial cell reactivity depended on the phase and severity of the pathological process in the experimental allergic encephalomyelitis induced in guinea pigs by injection of Mycobacteria tuberculosis in a mixture of arlacel and vaselin. These reactivity changes measured by the method of inhibition of the glial cell migration in the tissue culture was specific of the nervous tissue antigens. The same changes in the reactivity could be induced in the tissue culture of the glial cells from the intact animals by the addition of sera or the lymph node cells from the actively sensitized guinea pigs. The present data did not allow to attribute the changes in the glial cell reactivity to the products of destruction of the nervous tissue only to the action of the humoral or the cell factors (elements) penetrating into the CNS from the blood vessels or the lymphatic tissue.