Fluorescence-guided identification and dissection of retroperitoneal lymphomas (with video).

Surgery, especially if minimally invasive, still plays a role in the diagnosis of suspect lymphoproliferative lesions in challenging locations such as the retroperitoneum. Fluorescence guidance may help in such cases facilitating the visualization of highly vascularized lesions. Our recent experience with a 71-year-old woman with retroperitoneal lymphadenopathy and suspected lymphoma supports this hypothesis. A solution of indocyanine green (ICG) intravenously administered at the induction of anesthesia helped identify and dissect the lymphadenopathy. Histology confirmed follicular B cell lymphoma. This case supports the growing role of ICG fluorescence in guiding minimally invasive surgeries for lymphoproliferative diseases, offering a potential alternative to more complex preoperative and intraoperative ICG administration techniques.