Journal of Indian Association of Pediatric Surgeons · 2025
Germ Cell Neoplasia In situ in Undescended Testis: A Myth or Reality?
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Mishra Pravash Ranjan, Purkait Suvendu, Manekar Aditya Arvind, Tripathy Bikasha Bihary
Аннотация
BACKGROUND: Untreated cryptorchid testes are in risk of intratubular germ cell neoplasia and subsequently may give rise to invasive germ cell tumors.
MATERIALS AND METHODS: Tissue samples were obtained from patients undergoing orchidectomy or orchiopexy and were subjected to routine histopathological and immunohistochemical examinations.
RESULTS: Forty-three patients were enrolled in this study out of which 30 samples were collected. The mean age of patients was 9.16 years. One case (6.7%) showed positivity of the germ cell neoplasia with anto placental alkaline phosphatase and Anto CD-117 positive. Other histopathological findings such as fibrocollagenous tissue and Leydig cell hyperplasia were reported.
CONCLUSION: Early surgical management is of importance for a better outcome in cases of undescended testes.
MATERIALS AND METHODS: Tissue samples were obtained from patients undergoing orchidectomy or orchiopexy and were subjected to routine histopathological and immunohistochemical examinations.
RESULTS: Forty-three patients were enrolled in this study out of which 30 samples were collected. The mean age of patients was 9.16 years. One case (6.7%) showed positivity of the germ cell neoplasia with anto placental alkaline phosphatase and Anto CD-117 positive. Other histopathological findings such as fibrocollagenous tissue and Leydig cell hyperplasia were reported.
CONCLUSION: Early surgical management is of importance for a better outcome in cases of undescended testes.