Reactivation of Cytomegalovirus in Colonic Tuberculosis in an Immunocompetent Patient.

Cytomegalovirus (CMV) reactivation in Mycobacterium tuberculosis (TB) infection is rare and has been only reported in immunocompromised patients. In this case report, we describe a patient with Type 2 diabetes with acute on chronic abdominal pain found to have miliary TB with terminal ileitis and ascending colon ulcers with biopsy-positive TB and CMV. The decision was made not to treat the local CMV reactivation, and he improved solely on standard drug-susceptible antituberculous therapy. This is the first reported case of gastrointestinal TB and CMV coinfection in a patient without known classic immunodeficiency.