Availability and Costs of Allergic Rhinitis Treatments Across the World: A Survey of ARIA Experts.
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Urbano Maria Clara, Vieira Rafael José, Xiang Yi-Kui, Gil-Mata Sara, Bedbrook Anna, Abdullah Baharudin, Al-Ahmad Mona, Al-Nesf Maryam Ali, Alvarez-Cuesta Emilio, Amade Salma Mussagy, Asllani Julijana, Bennoor Kazi S, Berghea Elena Camelia, Calvo-Gil Mario, Caraballo Luis R, Castro Elizabeth, Cecchi Lorenzo, Choudhury Deepa, Christoff George, Chu Derek K, Cirule Ieva, Cruz Alvaro A, Dokic Dejan, Gemicioglu Bilun, Guzman Maria Antonieta, Grisle Ineta, Haahtela Tari, Hossny Elham, Hoetzenecker Wolfram, Hrubisko Martin, Iinuma Tomohisa, Ispayeva Zhanat, Ivancevich Juan Carlos, Ko Fanny Wai San, Kraxner Helga, Kupczyk Maciej, Kvedariene Violeta, Lam Yen, Larenas-Linnemann Désirée E, Mahboub Bassam, Mahesh Padukudru A, Masjedi Mohammed Reza, McDonald Garry, Melendez Amarilis, Mihaltan Florin, Milenkovic Branislava, Mohammad Yousser, Niedoszytko Marek, O'Hehir Robyn E, Panaitescu Carmen, Panzner Petr, Papadopoulos Nikolaos G, Perez José Miguel Fuentes, Pham-Thi Nhân, Pitsios Constantinos, Plavec Davor, Repka-Ramirez María Susana, Romantowski Jan, Rostan Marylin Valentin, Rottem Menachem, Salim Hani, Tantilipikorn Pongsakorn, Tomic-Spiric Vesna, Valiulis Arunas, Vecillas Leticia de Las, Ventura Maria Teresa, Wallace Dana, Werminghaus Pascal, Williams Sian, Zamora Francisco Javier Plaza, Klimek Ludger, Zuberbier Torsten, Pereira Ana Margarida, Fonseca João A, Bousquet Jean, Sousa-Pinto Bernardo
Аннотация
METHODS: We sent a survey to members of the Allergic Rhinitis and its Impact on Asthma (ARIA) group, asking for the availability and the lowest cost of specific allergic rhinitis medications in their respective countries. Data in local currencies were converted to 2024 US Dollars adjusted for Purchasing Power Parity (PPP). We compared the costs of different medication classes, assuming, for each class, the least expensive drug in each country, as well as full treatment adherence.
RESULTS: We received responses from ARIA experts in 51 different countries. Intranasal corticosteroids (INCS) and oral antihistamines (OAH) were available in all countries, but this was not observed for intranasal antihistamines (INAH) or for INAH+INCS. In most countries, OAH was the least costly drug class, while INAH+INCS was the most expensive. Among INCS, beclomethasone was the medication most frequently identified as the cheapest, while cetirizine and loratadine were the OAH most frequently reported as the least expensive. Among INAH+INCS, azelastine-fluticasone was more frequently identified as less costly than olopatadine-mometasone.
CONCLUSION: There is an important across-country and across-class variability in terms of costs of allergic rhinitis medications. The results of this study will inform the ARIA-EAACI 2024-2025 guidelines.