Медицинская библиотека · Muscle & nerve · 2017

Single-fiber EMG with concentric electrodes in lambert-eaton myasthenia.

Guan Yuzhou, Ding Qingyun, Liu Mingsheng, Niu Jingwen, Cui Liying

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Аннотация

INTRODUCTION

We analyzed jitter recordings made with concentric needle electrode (CNE) single-fiber electromyography (SFEMG) in Lambert-Eaton myasthenia (LEM).

METHODS

Fifteen subjects diagnosed with LEM were studied using CNE-SFEMG in the extensor digitorum (ED) and tibialis anterior (TA) muscles. CNE-SFEMG in the ED and TA was also used to evaluate 12 and 10 healthy controls (HCs), respectively.

RESULTS

Ten men and 5 women were diagnosed with LEM based on an increase of 100% in compound muscle action potential amplitude during 50 Hz repetitive nerve stimulation. All patients exhibited markedly greater jitter in the ED (88.8 ± 23.2 µs) and TA (92.2 ± 30.2 µs) than HCs (28.3 ± 3.4 µs and 30.9 ± 5.1 µs, respectively).

CONCLUSIONS

CNE-SFEMG is sensitive for discovering abnormalities in neuromuscular transmission in LEM. Muscle Nerve 56: 253-257, 2017.

Для цитирования: Guan Yuzhou, Ding Qingyun, Liu Mingsheng, Niu Jingwen, Cui Liying. Single-fiber EMG with concentric electrodes in lambert-eaton myasthenia.. Muscle & nerve. 2017. DOI: 10.1002/mus.25500.

Предметные рубрики MeSH

Action Potentials Adult Aged Electric Stimulation Electrodes Electromyography Fatigue Female Humans Immunoglobulins, Intravenous Lambert-Eaton Myasthenic Syndrome Male Middle Aged Muscle Fibers, Skeletal Muscle Weakness Neural Conduction Reflex Retrospective Studies Statistics, Nonparametric

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