Journal of the American Academy of Dermatology · 2019
Diffuse variants of scalp lichen planopilaris: Clinical, trichoscopic, and histopathologic features of 40 patients.
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Starace Michela, Orlando Gloria, Alessandrini Aurora, Baraldi Carlotta, Bruni Francesca, Piraccini Bianca Maria
Аннотация
BACKGROUND: Fibrosing alopecia in a pattern distribution and cicatricial pattern hair loss are poorly recognized diffuse variants of lichen planopilaris (LPP).
OBJECTIVES: The medical features of 40 patients affected by a diffuse hair thinning associated with a long-lasting history of pruritus and erythema of the scalp and a histopathologic diagnosis of LPP were reviewed.
METHODS: Clinical data, results of trichoscopy and histopathology, response to treatment, and follow-up were analyzed.
RESULTS: There were 18 patients diagnosed with fibrosing alopecia in pattern distribution and 2 patients with cicatricial pattern hair loss. A new variant of diffuse LPP, named "lichen planopilaris diffuse pattern," was described in 20 individuals.
LIMITATIONS: Low number of cases due to rarity of the diseases.
CONCLUSION: In patients complaining of a long-lasting history of scalp erythema, itching/dysesthesia, and diffuse hair thinning, it is advisable to consider diffuse variants of LPP.
OBJECTIVES: The medical features of 40 patients affected by a diffuse hair thinning associated with a long-lasting history of pruritus and erythema of the scalp and a histopathologic diagnosis of LPP were reviewed.
METHODS: Clinical data, results of trichoscopy and histopathology, response to treatment, and follow-up were analyzed.
RESULTS: There were 18 patients diagnosed with fibrosing alopecia in pattern distribution and 2 patients with cicatricial pattern hair loss. A new variant of diffuse LPP, named "lichen planopilaris diffuse pattern," was described in 20 individuals.
LIMITATIONS: Low number of cases due to rarity of the diseases.
CONCLUSION: In patients complaining of a long-lasting history of scalp erythema, itching/dysesthesia, and diffuse hair thinning, it is advisable to consider diffuse variants of LPP.
Предметные рубрики MeSH
5-alpha Reductase InhibitorsAdministration, OralAdministration, TopicalAdultAgedAlopecia AreataBiopsyCicatrixDermoscopyDisease ProgressionDrug Therapy, CombinationFemaleFibrosisFollow-Up StudiesHair FollicleHumansHydroxychloroquineImmunosuppressive AgentsInjections, SubcutaneousLichen PlanusMaleMiddle AgedRetrospective StudiesScalp DermatosesTreatment Outcome