The Journal of veterinary medical science · 2016
Comparison of cortisol and thyroid hormones between tuberculosis-suspect and healthy elephants of Nepal.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Paudel Sarad, Brown Janine L, Thapaliya Sharada, Dhakal Ishwari P, Mikota Susan K, Gairhe Kamal P, Shimozuru Michito, Tsubota Toshio
Аннотация
We compared cortisol and thyroid hormone (T3 and T4) concentrations between tuberculosis (TB)-suspected (n=10) and healthy (n=10) elephants of Nepal. Whole blood was collected from captive elephants throughout Nepal, and TB testing was performed using the ElephantTB STAT-PAK® and DPP VetTB® serological assays that detect antibodies against Mycobacterium tuberculosis and M. bovis in elephant serum. Cortisol, T3 and T4 were quantified by competitive enzyme immunoassays, and the results showed no significant differences in hormone concentrations between TB-suspect and healthy elephants. These preliminary data suggest neither adrenal nor thyroid function is altered by TB disease status. However, more elephants, including those positively diagnosed for TB by trunk wash cultures, need to be evaluated over time to confirm results.