Journal of veterinary internal medicine · 2026
In vivo radiographic characteristics associated with the mineral composition of calcium oxalate and struvite lower urinary tract uroliths in cats.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Pulido Vega Diego, Dalmon Thomas, Maurey Christelle, Mortier Jeremy
Аннотация
BACKGROUND: Radiography is widely used to diagnose lower urinary tract (LUT) urolithiasis in cats. Non-invasive identification of urolith mineral composition (UMC) is critical for therapy selection but remains challenging, as most data derive from dogs.
HYPOTHESIS/OBJECTIVES: To describe in vivo radiographic features of feline calcium oxalate and struvite LUT uroliths and identify distinguishing characteristics.
ANIMALS: Sixty-nine cats with LUT uroliths containing ≥70% of calcium oxalate (n = 45) or struvite (n = 24).
METHODS: Retrospective cross-sectional study. Radiographs were evaluated for urolith size, shape, surface, internal architecture, subjective radiopacity, and quantitative radiopacity, assessed using a ratio of urolith-to-L5 vertebra pixel values (UOR). Diagnostic performance of urolith size and UOR was assessed with receiver operating characteristic (ROC) curves, calculating the area under the ROC curve (AUC).
RESULTS: Struvite uroliths had lower quantitative radiopacity with a UOR cut-off ≤0.78 (AUC = 0.81, P < .001; sensitivity: 58%, specificity: 92%). They were larger, with a cut-off value of ≥7.3 mm (AUC = 0.75, P < .001; sensitivity: 38%, specificity: 98%), more frequently irregularly shaped, with rough surface and heterogeneous architecture. Urease-positive bacteriuria was present in 43% of struvite uroliths; infected struvite uroliths were significantly larger (median, 9.8 mm; interquartile range [IQR], 5.4-13 mm) than sterile ones (median, 4.6 mm; IQR, 2.6-5.4 mm; P = .02). Calcium oxalate uroliths were frequently smaller, more radiopaque, uniform, smooth, and associated with nephroliths.
CONCLUSIONS AND CLINICAL IMPORTANCE: In vivo radiographic characteristics aid in differentiating struvite from calcium oxalate LUT uroliths, selecting non-invasive therapy, and reducing unnecessary surgeries.
HYPOTHESIS/OBJECTIVES: To describe in vivo radiographic features of feline calcium oxalate and struvite LUT uroliths and identify distinguishing characteristics.
ANIMALS: Sixty-nine cats with LUT uroliths containing ≥70% of calcium oxalate (n = 45) or struvite (n = 24).
METHODS: Retrospective cross-sectional study. Radiographs were evaluated for urolith size, shape, surface, internal architecture, subjective radiopacity, and quantitative radiopacity, assessed using a ratio of urolith-to-L5 vertebra pixel values (UOR). Diagnostic performance of urolith size and UOR was assessed with receiver operating characteristic (ROC) curves, calculating the area under the ROC curve (AUC).
RESULTS: Struvite uroliths had lower quantitative radiopacity with a UOR cut-off ≤0.78 (AUC = 0.81, P < .001; sensitivity: 58%, specificity: 92%). They were larger, with a cut-off value of ≥7.3 mm (AUC = 0.75, P < .001; sensitivity: 38%, specificity: 98%), more frequently irregularly shaped, with rough surface and heterogeneous architecture. Urease-positive bacteriuria was present in 43% of struvite uroliths; infected struvite uroliths were significantly larger (median, 9.8 mm; interquartile range [IQR], 5.4-13 mm) than sterile ones (median, 4.6 mm; IQR, 2.6-5.4 mm; P = .02). Calcium oxalate uroliths were frequently smaller, more radiopaque, uniform, smooth, and associated with nephroliths.
CONCLUSIONS AND CLINICAL IMPORTANCE: In vivo radiographic characteristics aid in differentiating struvite from calcium oxalate LUT uroliths, selecting non-invasive therapy, and reducing unnecessary surgeries.