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DOI 10.1002/cnm.3636

Медицинская библиотека · International journal for numerical methods in biomedical engineering · 2022

Effects of different bypass surgeries on LSA revascularization in patients with left subclavian occlusion.

Li Da, Zeng Xiangguo, Wang Jiarong, Yuan Ding, Zheng Tinghui

Клинический случайСтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

INTRODUCTION

Left subclavian artery (LSA) bypass surgery is mainly carried out for patients with severe left subclavian occlusion. This article aimed to evaluate the hemodynamic effects of different surgical bypass modes on LSA revascularization.

METHODS

Three-dimensional models of the aorta were reconstructed from CTA images of a patient with LSA occlusion, a patient with type B aortic dissection with LSA coverage during thoracic endovascular aortic repair, and a healthy 74-year-old man, resulting in six modes for each person: healthy LSA mode, LSA occlusion mode and four bypass modes. Hemodynamic parameters, including flow field, flow distribution, pressure gradient, and wall shear stress, were calculated using computational fluid dynamics.

RESULTS

After LSA bypass surgery, distal LSA blood flow resulting from left common carotid artery (LCCA) to distal LSA bypass was 100% of that in the healthy mode, while the other modes yielded flows at least 91%. Moreover, reversed flow only completely disappeared with LCCA to distal LSA bypass, whereas reverse flow was observed in the other three modes in early systole.

CONCLUSION

Left common carotid artery to distal LSA bypass can effectively reduce reverse blood flow in the left vertebral artery, and it is a feasible, effective, and safe option for LSA revascularization in patients with left subclavian occlusion.

Для цитирования: Li Da, Zeng Xiangguo, Wang Jiarong, Yuan Ding, Zheng Tinghui. Effects of different bypass surgeries on LSA revascularization in patients with left subclavian occlusion.. International journal for numerical methods in biomedical engineering. 2022. DOI: 10.1002/cnm.3636.

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