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DOI 10.3389/fpara.2023.1195646

Медицинская библиотека · Frontiers in parasitology · 2023

Diagnosis and management of chagasic cardiomyopathy patients in several institutions in Argentina.

Chuit Roberto, Antonietti Laura, Agüero Roberto Nicolás, Varela Gabriela Badino, Mordini Oscar Daniel, Alemandri Emilce, Abril Marcelo, Días Miguel, Yadón Zaida E, Pizzi Hugo, Pizzi Rogelio

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Аннотация

INTRODUCTION

According to estimates by the World Health Organization, the infection and disease caused by the protozoan parasite Trypanosoma cruzi affects almost 6 million people, and more than 1 million suffer chagasic cardiomyopathy (Ch-CMP). It is estimated that 376,000 of these individuals live in Argentina. This study describes the characteristics and medical management of individuals with Ch-CMP in Argentina.

METHODS

This is a descriptive, retrospective, cross-sectional study on the diagnosis and clinical and therapeutic evaluation of patients with Ch-MCP using historical records collected from different medical institutions in the country between 1 January 2018 and 30 June 2021.

RESULTS

During this period, 652 patients (mean age 61.2 years ± 12.9) were included, with women accounting for 60.3% of the sample. The diagnosis of cardiac insufficiency was 36.0% and 64.4% had arrhythmias. The most common cardiovascular risk factors detected were arterial hypertension (69.5%), smoking (56.6%), and diabetes (20.9%). Less than half of the subjects (45.4%) had been studied by electrocardiogram (ECG), chest X-ray, and echocardiogram. ECG studies showed conduction disorders (38.8%), left ventricular hypertrophy (28.1%), ventricular extrasystoles (22.0%), complete right bundle branch block (8.6%), and atrioventricular block (2.6%). According to the Kuschnir classification, 21.4% of the study subjects were in Grade 3.

CONCLUSIONS

The patients included in the study had a similar clinical presentation and history of the disease to those published in other studies. When evaluating the medical practices, we found that patients were inadequately studied. Although it is difficult to estimate the fraction of the total number of patients represented by the present study, the study allowed us to establish that the care received by patients was not adequate.

Для цитирования: Chuit Roberto, Antonietti Laura, Agüero Roberto Nicolás, Varela Gabriela Badino, Mordini Oscar Daniel, Alemandri Emilce, Abril Marcelo, Días Miguel, Yadón Zaida E, Pizzi Hugo, Pizzi Rogelio. Diagnosis and management of chagasic cardiomyopathy patients in several institutions in Argentina.. Frontiers in parasitology. 2023. DOI: 10.3389/fpara.2023.1195646.
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