A topical cream containing a zinc gel (allergy guard) as a prophylactic against latex glove-related contact dermatitis.

BACKGROUND

Many health care workers are sensitized to the proteins in natural rubber latex and get contact dermatitis as a result of wearing latex gloves.

OBJECTIVE

The aim of the study was to evaluate a topical formulation containing a zinc gel (Allergy Guard) as a prophylactic against latex glove-related contact dermatitis.

METHODS

The study was carried out with volunteers who exhibited mild to moderate contact dermatitis (type IV) after wearing latex gloves as per the protocol.

RESULTS

Allergy Guard significantly reduced skin irritation in volunteers who exhibited type IV hypersensitivity when exposed to latex gloves. Allergy Guard also exhibited a barrier effect as shown by the permeation of chlorophyllin dye into the skin of volunteers. Allergy Guard prevented dermal irritation induced by sodium lauryl sulfate.

CONCLUSION

Topical formulations containing a zinc gel may be used to delay or prevent latex sensitivity, especially among health care professionals.