Journal of neurosurgical sciences · 2024
The role of MRgFUS in the treatment of neuropsychiatric disorders: a state of the art.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Campisi Benedetta M, Costanzo Roberta, Noto Manfredi, Cipollina Giuseppe P, Marino Silvia, DI Lorenzo Giuseppe, Bonosi Lapo, Brunasso Lara, Iacopino Domenico G, Maugeri Rosario
Аннотация
INTRODUCTION: Magnetic resonance-guided focused ultrasound (MRgFUS) is a contemporary non-invasive ablative procedure that utilizes high- or low-intensity ultrasound, guided and monitored by magnetic resonance imaging (MRI). While MRgFUS has been established as an effective treatment for conditions like essential tremor and tremor-dominant Parkinson's disease, it has recently emerged as a safe and promising ablative minimally invasive procedure for the management of treatment-resistant psychiatric disorders. Indeed, despite the availability of various pharmacological and behavioral therapies, a subset of psychiatric patients remains refractory to conventional treatments.
EVIDENCE ACQUISITION: To assess the feasibility and safety of MRgFUS in psychiatric disorders, a comprehensive literature search in PubMed and Scopus databases was conducted, resulting in the inclusion of five relevant articles in this review.
EVIDENCE SYNTHESIS: While data on this innovative procedure are still limited, MRgFUS demonstrates potential as a safer and less invasive surgical technique for treating these disorders.
CONCLUSIONS: Continued research efforts and data validation are imperative to establish MRgFUS as an additional, minimally invasive procedure for treatment-resistant psychiatric patients in the near future.
EVIDENCE ACQUISITION: To assess the feasibility and safety of MRgFUS in psychiatric disorders, a comprehensive literature search in PubMed and Scopus databases was conducted, resulting in the inclusion of five relevant articles in this review.
EVIDENCE SYNTHESIS: While data on this innovative procedure are still limited, MRgFUS demonstrates potential as a safer and less invasive surgical technique for treating these disorders.
CONCLUSIONS: Continued research efforts and data validation are imperative to establish MRgFUS as an additional, minimally invasive procedure for treatment-resistant psychiatric patients in the near future.