Prognostic capacity of the leuko-glycemic index in cardiac syndrome Y.

ObjectivesCardiac syndrome Y (CSY) phenomenon is characterized by the gradual opacification of the coronary vasculature at the distal level. The leuko-glycemic index (LGI) is a blood glucose and white blood cell count index. This study investigates the relationship between CSY and the leuko-glycemic index.MethodsA case-control, retrospective study was conducted. Consecutively selected individuals with complaints of angina were included in the study. Subjects with normal coronary flow (n = 132) and coronary slow flow (n = 136) were classified, after confirmation of coronary angiography results.ResultsThe age ranges were recorded as 57 (48-64) for the NCF group vs. 52 (46-58) for the CSY group, P = .010. The mean hematocrit (Hct), Hemoglobin (Hg), White blood cells (WBC), and LGI were significantly higher in the CSY group than in the normal coronary flow group (P < .001). Accordingly, CSY was positively correlated with Hct, Hg, and WBC (P < .001). ROC curve analysis indicated that a cut-off value of ≥9.28 for the LGI predicted CSF with a sensitivity of 78% and a specificity of 78.1% [Area under the curve (AUC): 0.626 and 95% CI: 0.559-0.693].ConclusionsIn this study, we show for the first time that elevated LGI levels can independently predict CSF formation in the subclinical process.