Head & neck · 2026
A Novel Connector for Intraoperative Nerve Monitoring Probes in Endoscopic Thyroidectomy: Comparative Efficacy and Preclinical Evaluation in a Porcine Model.
СтатьяСравнительное исследованиеПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Chairat Parnwad, Pithuksurachai Paveena, Chongkolwatana Cheerasook, Wechakarn Pongsakorn, Akkhawattanangkul Yada, Hommuang Kewvaree, Charoonrut Phingphol, Jamikorn Tanyanan, Anuwong Angkoon, Wu Che-Wei, Randolph Gregory W, Russell Marika D, Abdelhamid Ahmed Amr H, Maneeprasopchoke Prachya
Аннотация
BACKGROUND: This study aimed to develop a connector that adapts standard endoscopic instruments into functional nerve stimulator probes.
METHODS: The connector underwent engineering validation in a laboratory and preclinical testing using a porcine model. A handheld standard stimulator probe served as the control. The experimental group consisted of a long monopolar probe and two connector-adapted probes. Recurrent laryngeal nerve (RLN) and vagus nerves were stimulated to compare the efficacy and safety of the adapted probes with the standard probe.
RESULTS: The connector, when coupled to endoscopic instruments, did not show a statistically significant difference in electromyographic (EMG) amplitude at 1 mA stimulation compared with the standard probe. Safety analysis showed no significant hemodynamic effects.
CONCLUSION: This proof-of-concept study demonstrates that the developed connector, when paired with endoscopic instruments, enables reliable nerve identification and preservation during endoscopic thyroid surgery, with favorable efficacy and safety profiles.
METHODS: The connector underwent engineering validation in a laboratory and preclinical testing using a porcine model. A handheld standard stimulator probe served as the control. The experimental group consisted of a long monopolar probe and two connector-adapted probes. Recurrent laryngeal nerve (RLN) and vagus nerves were stimulated to compare the efficacy and safety of the adapted probes with the standard probe.
RESULTS: The connector, when coupled to endoscopic instruments, did not show a statistically significant difference in electromyographic (EMG) amplitude at 1 mA stimulation compared with the standard probe. Safety analysis showed no significant hemodynamic effects.
CONCLUSION: This proof-of-concept study demonstrates that the developed connector, when paired with endoscopic instruments, enables reliable nerve identification and preservation during endoscopic thyroid surgery, with favorable efficacy and safety profiles.