Combined RF and Gradient Effects on Unintended Vagus Nerve Stimulation from Cuff Electrodes Under MRI.

In this work, we studied the combined effects of MR emissions, including gradient-induced electric fields and radiofrequency-induced heating, on vagus nerve activation in the presence of a cuff electrode. Our approach integrates electromagnetic and thermal simulations and neurophysiological modeling to assess these interactions. Preliminary results indicate that the radiofrequency-induced heating of the cuff electrode can further alter the activation threshold in the specific configuration investigated.Clinical Relevance- This study highlights the potential for radiofrequency-induced heating to lower the activation threshold, potentially leading to unintended vagus nerve stimulation, which may have safety implications for patients with implanted cuff electrodes.