Neurogastroenterology and motility · 2026
Magnesium-Rich Mineral Water Improves Stool Consistency and Bowel Habits in Healthy Subjects: A Randomized Controlled Trial.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Yoneda Hideki, Tomita Toshihiko, Kitano Takayuki, Morishita Daisuke, Kodani Mio, Nishii Norio, Sei Hiroo, Eda Hirotsugu, Sato Toshiyuki, Kawai Mikio, Yokoyama Yoko, Igeta Masataka, Okugawa Takuya, Fukui Hirokazu, Shinzaki Shinichiro
Аннотация
INTRODUCTION: Magnesium-rich mineral water influences stool consistency and bowel habits. However, randomized controlled trials directly comparing magnesium-rich mineral water with soft water using standardized bowel outcomes remain limited.
METHODS: This single-center, randomized, parallel-group trial enrolled 40 healthy subjects who did not meet Rome IV criteria for chronic constipation or irritable bowel syndrome. After a 7-day observation period, participants consumed either soft water or magnesium-rich mineral water (1 L/day) for 14 days. The primary endpoint was change in weekly mean Bristol Stool Form Scale (BSFS) score from baseline to intervention week 2, analyzed using analysis of covariance. Secondary endpoints included spontaneous bowel movements (SBM; bowel movements without rescue medication), complete spontaneous bowel movements (CSBM; SBM with a sensation of complete evacuation), subjective global improvement, time to first SBM, and daily total fluid intake.
KEY RESULTS: All participants completed the trial. Compared with soft water, magnesium-rich mineral water significantly increased BSFS score at week 1 and week 2 (both p < 0.05). Weekly frequencies of SBM and CSBM were higher in the magnesium-rich mineral water group. Subjective improvement at week 2 was more frequent with magnesium-rich mineral water. Compared with the observation period, no difference in water intake was observed between the two groups.
CONCLUSIONS AND INFERENCES: In healthy subjects, magnesium-rich mineral water was associated with stool softening and increased bowel movement frequency. No safety concerns were observed during the study period. These findings support further investigation of magnesium-rich mineral water as a strategy for modulating bowel habits.
METHODS: This single-center, randomized, parallel-group trial enrolled 40 healthy subjects who did not meet Rome IV criteria for chronic constipation or irritable bowel syndrome. After a 7-day observation period, participants consumed either soft water or magnesium-rich mineral water (1 L/day) for 14 days. The primary endpoint was change in weekly mean Bristol Stool Form Scale (BSFS) score from baseline to intervention week 2, analyzed using analysis of covariance. Secondary endpoints included spontaneous bowel movements (SBM; bowel movements without rescue medication), complete spontaneous bowel movements (CSBM; SBM with a sensation of complete evacuation), subjective global improvement, time to first SBM, and daily total fluid intake.
KEY RESULTS: All participants completed the trial. Compared with soft water, magnesium-rich mineral water significantly increased BSFS score at week 1 and week 2 (both p < 0.05). Weekly frequencies of SBM and CSBM were higher in the magnesium-rich mineral water group. Subjective improvement at week 2 was more frequent with magnesium-rich mineral water. Compared with the observation period, no difference in water intake was observed between the two groups.
CONCLUSIONS AND INFERENCES: In healthy subjects, magnesium-rich mineral water was associated with stool softening and increased bowel movement frequency. No safety concerns were observed during the study period. These findings support further investigation of magnesium-rich mineral water as a strategy for modulating bowel habits.