Magnesium-Rich Mineral Water Improves Stool Consistency and Bowel Habits in Healthy Subjects: A Randomized Controlled Trial.
Аннотация
INTRODUCTION
Magnesium-rich mineral water influences stool consistency and bowel habits. However, randomized controlled trials directly comparing magnesium-rich mineral water with soft water using standardized bowel outcomes remain limited.
METHODS
This single-center, randomized, parallel-group trial enrolled 40 healthy subjects who did not meet Rome IV criteria for chronic constipation or irritable bowel syndrome. After a 7-day observation period, participants consumed either soft water or magnesium-rich mineral water (1 L/day) for 14 days. The primary endpoint was change in weekly mean Bristol Stool Form Scale (BSFS) score from baseline to intervention week 2, analyzed using analysis of covariance. Secondary endpoints included spontaneous bowel movements (SBM; bowel movements without rescue medication), complete spontaneous bowel movements (CSBM; SBM with a sensation of complete evacuation), subjective global improvement, time to first SBM, and daily total fluid intake.
KEY
RESULTS
All participants completed the trial. Compared with soft water, magnesium-rich mineral water significantly increased BSFS score at week 1 and week 2 (both p < 0.05). Weekly frequencies of SBM and CSBM were higher in the magnesium-rich mineral water group. Subjective improvement at week 2 was more frequent with magnesium-rich mineral water. Compared with the observation period, no difference in water intake was observed between the two groups.
CONCLUSIONS AND INFERENCES: In healthy subjects, magnesium-rich mineral water was associated with stool softening and increased bowel movement frequency. No safety concerns were observed during the study period. These findings support further investigation of magnesium-rich mineral water as a strategy for modulating bowel habits.
Предметные рубрики MeSH
Подготовка и перевод публикации
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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