Studies on experimental mixed infection of Schistosoma haematobium and Schistosoma mansoni in the albino mouse.

Swiss albino mice have been infected with S. haematobium and challenged with S. mansoni. No apparent disturbances as regards worm load and oviposition were observed. Yet certain deviations in the egg-distribution sites for both species were found. They were attributed to the possibility of earlier de-development of collateral circulation. Cross-pairing between the two species was met with, which might explain the extra number of S. haematobium eggs found in the small intestine. Although no major effect has been revealed, no conclusion at this stage could be put forward as regards complete absence of cross-immunity.