Nutrition (Burbank, Los Angeles County, Calif.) · 2026
Associations of dietary diversity with constipation symptoms and gut microbiota features in individuals with functional constipation.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Tang Amei, Tian Tian, Li Wei, Li Yunfeng, Lai Hao, Wang Menghan, He Juan, Feng Xinran, He Chen, He Yifei, Jia Kaizhen, Ma Guoqing, Liu Xin
Аннотация
OBJECTIVES: Functional constipation (FC) is prevalent worldwide and is an increasingly prominent problem among Chinese. Dietary modifications are recommended for FC, yet little is known about the impact of dietary diversity and the relevance of the gut microbiota. The aim of this study was to evaluate the relationship between dietary diversity and constipation symptoms and gut microbiota profiles among individuals with FC.
METHODS: This was a cross-sectional study among 250 participants with FC aged 18 to 70 y. Dietary intake was assessed using food frequency questionnaires. Dietary diversity score (DDS) was calculated based on the intake frequencies of food categories, ranging from 0 (low DDS) to 8 (high DDS). Gut microbiota was measured using a 16S ribosomal RNA amplification method.
RESULTS: In our participants with FC, DDS was positively associated with bowel movement frequency (BMF) (P = 0.012 for trend). Among all of the genera evaluated (121 in total), the Ruminococcus torques group was inversely correlated with BMF (β = -0.901, P < 0.001, false discovery rate P = 0.022) and potentially correlated with DDS (β = -0.142, P = 0.029, false discovery rate P = 0.116). Additionally, the genera distribution of gut microbial enterotypes differed by DDS level and weekly BMF.
CONCLUSIONS: In individuals with FC, high dietary diversity was associated with relief of constipation involving gut microbiota alterations.
METHODS: This was a cross-sectional study among 250 participants with FC aged 18 to 70 y. Dietary intake was assessed using food frequency questionnaires. Dietary diversity score (DDS) was calculated based on the intake frequencies of food categories, ranging from 0 (low DDS) to 8 (high DDS). Gut microbiota was measured using a 16S ribosomal RNA amplification method.
RESULTS: In our participants with FC, DDS was positively associated with bowel movement frequency (BMF) (P = 0.012 for trend). Among all of the genera evaluated (121 in total), the Ruminococcus torques group was inversely correlated with BMF (β = -0.901, P < 0.001, false discovery rate P = 0.022) and potentially correlated with DDS (β = -0.142, P = 0.029, false discovery rate P = 0.116). Additionally, the genera distribution of gut microbial enterotypes differed by DDS level and weekly BMF.
CONCLUSIONS: In individuals with FC, high dietary diversity was associated with relief of constipation involving gut microbiota alterations.