Imaging Pitfalls in Evaluating Liver Metastases in Breast Cancer With Autosomal Dominant Polycystic Kidney Disease-Associated Polycystic Liver: A Case Report.

Extensive hepatic cysts in ADPKD, together with a diffuse infiltrative liver metastatic pattern, can lead to radiological underestimation of hepatic tumor burden on conventional whole-body imaging. Persistent biomarker-imaging discordance should prompt reassessment of disease progression at known sites and involvement of other organs, with organ-specific imaging when clinically indicated.