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DOI 10.1093/ecco-jcc/jjaf208

Медицинская библиотека · Journal of Crohn's & colitis · 2026

From resection to preservation: redefining the surgical paradigm in Crohn's disease.

Migliorisi Giulia, Delaplace Raphaëlle, Honap Sailish, Germain Adeline, Mouillot Thomas, Peyrin-Biroulet Laurent, Kotze Paulo G

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Аннотация

Surgery is a pivotal component of the management of Crohn's disease (CD), particularly in cases of disease-related complications or failure of medical therapy. However, the risk of short bowel syndrome following multiple large resections makes bowel preservation strategies a major therapeutic priority. This review gathers insights from a diverse group of inflammatory bowel disease specialists, exploring the full spectrum of bowel-preserving strategies, from conservative surgical techniques and peri-operative optimization to emerging innovations in robotic surgery. The therapeutic paradigm of treat-to-target and tight disease monitoring is shifting the focus from reactive interventions to proactive and personalized care. Looking ahead, the evolving implementation of multi-omics profiling and artificial intelligence holds promise to reshape the role of surgery in CD. Surgery should no longer be viewed solely as a response to complications, but rather as an individualized, biology-driven strategy that prioritizes bowel preservation. In this rapidly advancing field, innovation is measured not only by clinical outcomes but also by every centimeter of bowel preserved.

Для цитирования: Migliorisi Giulia, Delaplace Raphaëlle, Honap Sailish, Germain Adeline, Mouillot Thomas, Peyrin-Biroulet Laurent, Kotze Paulo G. From resection to preservation: redefining the surgical paradigm in Crohn's disease.. Journal of Crohn's & colitis. 2026. DOI: 10.1093/ecco-jcc/jjaf208.

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