Alterations of thyroid and adipose tissue hormones in acute and convalescent COVID-19 patients.

OBJECTIVE

Aim: To study and analyze studies data of thyroid function and adipose tissue hormones changes in patients with coronavirus infection.

PATIENTS AND

METHODS

Materials and

Methods

The study was conducted on the basis of the Clinical Hospital «CMCH», Uzhhorod, outpatient department. The clinical presentation of the patients with Covid-19 verified diagnosis of was represented by damage to the upper respiratory tract, in particular nasopharyngitis. The age of the studied patients was 18±2.15 years.

RESULTS

Results

All thyroid status parameters varied within the reference values, but it is noteworthy that after treatment, a significant increase in TSH levels was observed both after treatment and in comparison with the control group (p1#60;0.01; p3#60;0.01) and after 6 months шт 3.1 times (p2#60;0.01; p4#60;0.01). Representative dynamic values of ATPO were identified both after treatment and in comparison with the control group (p1#60;0.01; p3<0.01) and after 6 months. A significant decrease in ATPO was observed in 4.7 times (p2#60;0.01; p4#60;0.01). All levels of the studied adiponectin, leptin and C-peptide parameters varied within the reference range. Adiponectin values significantly decreased after treatment and after 6 months (p4<0.01) in 4 times; Leptin levels significantly decreased after treatment in 2.8 times and after 6 months - in 3 times (p4#60;0.01). C-peptide values (p4=0.12) reached the level of the control group.

CONCLUSION

Conclusions

Investigation of thyroid function and adipose tissue hormones changes in patients with Covad-19 was conducted. All thyroid status parameters and adipose tissue hormones varied within the reference values with different variations.