Endoscopic Management of Sinonasal Ossifying Fibroma: Clinical Experience From a Single Institution.

BACKGROUND

Sinonasal ossifying fibroma (OF) is a rare benign fibro-osseous tumor that can cause locally aggressive disease of the paranasal sinuses and skull base. Data on the outcomes after contemporary endoscopic management remain limited.

METHODS

We retrospectively reviewed patients with pathologically confirmed sinonasal OF diagnosed at a tertiary referral center. Seven patients were included in this study. Four patients who underwent definitive endoscopic endonasal surgery with complete resection and postoperative follow-up were included in the outcome analyses.

RESULTS

The lesions arose from the ethmoid sinus (n=2), maxillary sinus (n=1), and sphenoid sinus (n=1). All tumors had well-defined margins and a mixed-density pattern on computed tomography. All patients underwent endoscopic endonasal resection with complete excision. After a median follow-up of 24 months (range: 3-69 mo), no recurrence was observed, and none showed evidence of disease during the last follow-up.

CONCLUSION

Complete endoscopic resection of the sinonasal OF achieved excellent short- to mid-term disease control without major morbidity.