Reddish/bluish benign lesions evaluated by dermus SkinScanner.

Angiomas and blue nevi are common benign skin lesions with overlapping clinical appearances that can mimic malignancy, such as melanoma. This study evaluates the role of dermoscopy-assisted high-frequency ultrasound (DA-HFUS) in characterizing these lesions. Five cases (2 angiomas, 3 blue nevi) were examined using the Dermus SkinScanner, a handheld 33 MHz device with integrated optical guidance. Dermoscopy revealed blue nevi as regular, slate blue or brown lesions, occasionally with white veils; angiomas appeared as blue-purple papules with homogeneous purple lacunes. On ultrasound, blue nevi were well-demarcated, hypoechoic lesions with occasional hyperechoic foci suggestive of fibrosis, while angiomas showed heterogeneous echotexture with mixed echogenicity reflecting vascular and fibrous components. Fibrotic blue nevi exhibited deep dermal extensions and hyperechogenic columns not visible on dermoscopy. These findings highlight the complementary role of DA-HFUS and dermoscopy in non-invasive diagnosis and structural assessment of benign pigmented lesions.