Journal of medical imaging and radiation sciences · 2026
MR guided uncertainty quantification of tumour motion in open face masks versus closed face masks in head and neck radiotherapy.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Tallon James, Nelder Claire, Dobby Benedict, Greenwood-Wilson Alice, Bailey Rachael, Dubec Michael, McPartlin Andrew, Gaffney John, van Herk Marcel, Choudhury Ananya, Eccles Cynthia L
Аннотация
PURPOSE: To assess positional reproducibility and tumour motion using standard of care (SoC) masks versus open face masks (OF) on an MR Linac (MRL) in head and neck (H&N) cancer radiotherapy (RT).
MATERIALS/METHODS: Four H&N cancer patients, oral cavity (n = 1), and oropharynx (n = 3) undergoing RT (60-66 Gy in 20-30 #) consented to an ethics approved imaging study. Patients underwent three MRI sessions on a 1.5 T MR Linac (Elekta, Sweden) that included six dynamic T2-weighted Fast Spin Echo 3D images acquired over an 8-minute period during the first, middle and final week of RT. Patients were imaged to compare the OF mask to SoC mask. Each dynamic image (n = 6) was registered to the first image, to assess tumour motion using rigid registration performed by three observers. A clip box was used to establish rotations and translations in the tumour region of interest (ROI). Intra and inter-fraction tumour motion were calculated over the three sessions.
RESULTS: Intra-fraction tumour motion was greater in X (pitch) and Z (yaw) rotations when wearing an OF mask compared to SoC, however displacements were within institutional tolerances. Translations were similar for both immobilisation devices.
CONCLUSIONS: A small intra fraction tumour motion increase was seen with the OF mask, but all displacements were within institutional tolerances. Larger cohort studies are needed to improve strength of this work.
MATERIALS/METHODS: Four H&N cancer patients, oral cavity (n = 1), and oropharynx (n = 3) undergoing RT (60-66 Gy in 20-30 #) consented to an ethics approved imaging study. Patients underwent three MRI sessions on a 1.5 T MR Linac (Elekta, Sweden) that included six dynamic T2-weighted Fast Spin Echo 3D images acquired over an 8-minute period during the first, middle and final week of RT. Patients were imaged to compare the OF mask to SoC mask. Each dynamic image (n = 6) was registered to the first image, to assess tumour motion using rigid registration performed by three observers. A clip box was used to establish rotations and translations in the tumour region of interest (ROI). Intra and inter-fraction tumour motion were calculated over the three sessions.
RESULTS: Intra-fraction tumour motion was greater in X (pitch) and Z (yaw) rotations when wearing an OF mask compared to SoC, however displacements were within institutional tolerances. Translations were similar for both immobilisation devices.
CONCLUSIONS: A small intra fraction tumour motion increase was seen with the OF mask, but all displacements were within institutional tolerances. Larger cohort studies are needed to improve strength of this work.