[Histological and morphological characteristics of the different stages of cervical glandular intraepithelial neoplasia].

Currently there is no world system classification of glandular hyperplasia of uterine cervix (endocervix). Different authors give nonmonosemantic estimations to each type of cervical hyperplasia. Cervical Glandular Intraepithelial Neoplasia (CGIN) or Glandular Dysplasia is considered as a precancerous lesion of endocervix. Morphometric investigations have shown that for estimation of the degree of the endocervical glandular and intraepithelial neoplasia it is necessary the quantitative evaluation of the following criteria: type of epithelium--prismal, columnar, estimation of nucl/cytopl index >1, <1, =1, stratification, hyperchromatosis, hypochromatosis, big nucleoli, small nucleoli, stromal/parenchimal index >1, <1, =1. Based on our observations we suppose that glandular neoplasia must be divided into low grade intraepithelial neoplasia -CGIN 1, and high grade intraepithelial neoplasia -CGIN 2, and CGIN 3.