Impact of submucous myoma on the severity of anemia.

OBJECTIVE

To analyze the impact of the diameter (myoma-φ) and the uterine cavity protruding proportion (protruding %) of the submucous myoma on serum hemoglobin (Hb) level.

DESIGN

Retrospective descriptive study.

SETTING

Tertiary university hospital.

PATIENT(S): Two hundred fifty-nine women with a single submucous myoma.

INTERVENTION(S): Transvaginal ultrasound examination and office hysteroscopy.

MAIN OUTCOME MEASURE(S): Myoma-φ and protruding % were determined with transvaginal ultrasound scan and office hysteroscopy. Menorrhagic period (months) and serum Hb were recorded within 2 weeks of these examinations.

RESULT(S): Serum Hb negatively correlated with myoma-φ, protruding %, and menorrhagic period. The negative association between serum Hb and protruding % was even more prominent after adjusting for myoma-φ. Multivariate regression analysis revealed that myoma-φ and protruding %, after adjusting for the confounding effect of menorrhagic period, maintained a strongly negative correlation with serum Hb level. When myoma-φ was <2 cm, however, the serum Hb levels were similar regardless of the protruding %.

CONCLUSION(S): For women with a single submucous myoma, myoma-φ and protruding % can determine the serum Hb level significantly . As myoma-φ and protruding % increased, the serum Hb level decreased accordingly.