Synchronous Papillary Thyroid Microcarcinoma and Chronic Lymphocytic Leukemia: A Rare Interdisciplinary Case.

Papillary thyroid microcarcinoma is a common incidental finding due to the widespread use of high-resolution ultrasound imaging. Cervical lymphadenopathy, however, may have diverse etiologies, including metastatic disease and hematologic malignancies. We report a rare case of synchronous papillary thyroid microcarcinoma and chronic lymphocytic leukemia (CLL) presenting with cervical lymphadenopathy. The patient described in this case report underwent total thyroidectomy with left lateral neck dissection due to suspicious bilateral thyroid nodules and enlarged cervical lymph nodes. Histopathological examination confirmed papillary microcarcinoma, while additional immunohistochemical analysis of lymph nodes revealed a low-grade B-cell non-Hodgkin lymphoma consistent with CLL. This case highlights the importance of considering alternative diagnoses in patients with lymphadenopathy and emphasizes the role of thorough histopathological evaluation in guiding appropriate management.