Xenografts and platelet-rich fibrin impact on maxillary sinus augmentation: A comparative clinical histomorphometric study.

Insufficient posterior maxillary bone height limits implant placement in atrophic ridges. Therefore, it is of interest to compare deproteinized bovine bone mineral (DBBM) versus DBBM with advanced platelet-rich fibrin (A-PRF) in 60 sinuses across 30 patients undergoing lateral window sinus augmentation. Histomorphometry showed greater new bone formation [42.8 (6.4%) vs. 31.2 (5.9%), p=0.001] and less residual graft [28.4 (4.7) vs. 41.6 (6.1%), p=0.001] in the A-PRF group. Test sites also demonstrated improved bone density, graft height stability and 100% implant survival at 9 months. A-PRF accelerates bone regeneration and reduces graft resorption in sinus augmentation, advancing biologic augmentation strategies.