Internal medicine (Tokyo, Japan) · 2024
Unresectable Ulcerative Colitis Associated Colon Cancer in a Young Japanese Patient.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
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Hayashi Ryunosuke, Ueno Nobuhiro, Watanabe Hiromu, Kobayashi Yu, Sakatani Aki, Takahashi Keitaro, Yuzawa Sayaka, Ando Katsuyoshi, Tani Chikayoshi, Kashima Shin, Shonaka Tatsuya, Moriichi Kentaro, Tanabe Hiroki, Tanino Mishie, Fujiya Mikihiro
Аннотация
We herein present the case of a 30-year-old Japanese male patient with ulcerative colitis (UC) who was admitted to our hospital because of significant ascites. Upon evaluation, the patient was diagnosed with unresectable UC-associated colon cancer (UCAC), localized in the transverse colon. Using gene profiling of the tumor tissue, anti-epidermal growth factor receptor (EGFR) antibody combination chemotherapy was selected. Subsequently, the patient exhibited a temporary response to this regimen, with an enhancement in his quality of life and he was able to survive for 12 months. This case underscores the potential benefits of aggressive chemotherapy tailored to the gene profile in UCAC treatment, offering insights into potential avenues for improving the patient prognosis.