Pathologie (Heidelberg, Germany) · 2022
Histiocytic and dendritic cell neoplasms.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Pileri Stefano A, Melle Federica, Motta Giovanna, Tabanelli Valentina
Аннотация
BACKGROUND: Histiocytic and dendritic cell neoplasms (HDCNs) represent very rare tumors, which have been the subject of debate during the last few years.
OBJECTIVES: We aimed to provide a comprehensive review of the subject.
MATERIALS AND METHODS: The experience gained by the authors in large international studies and as a national reference center has been summarized to highlight the characteristics of each entity.
RESULTS: The clinical, morphologic, phenotypic, and molecular data of the different entities included under the heading of HDCNs are extensively discussed.
CONCLUSION: Currently, HDCNs are classified in the group of orphan diseases for which a standardized therapy is lacking. An international registry would facilitate expansion and dissemination of knowledge of these diseases and improve their treatment.
OBJECTIVES: We aimed to provide a comprehensive review of the subject.
MATERIALS AND METHODS: The experience gained by the authors in large international studies and as a national reference center has been summarized to highlight the characteristics of each entity.
RESULTS: The clinical, morphologic, phenotypic, and molecular data of the different entities included under the heading of HDCNs are extensively discussed.
CONCLUSION: Currently, HDCNs are classified in the group of orphan diseases for which a standardized therapy is lacking. An international registry would facilitate expansion and dissemination of knowledge of these diseases and improve their treatment.