Simultaneous duodenal and ileocolic obstruction in Crohn's disease: a case report.

Duodenal involvement in Crohn's disease (CD) is a rare phenomenon, often presenting with significant diagnostic and therapeutic challenges. We report the case of a male patient in his early 50s with longstanding CD and prior right hemicolectomy who presented with subacute obstructive symptoms, severe weight loss, and failure of medical therapy including corticosteroids and biologics. Imaging revealed strictures in both the duodenum and the ileocolic anastomosis site. Surgical intervention involved resection of the strictured duodenal segment with duodenojejunostomy and ileocolic resection with primary anastomosis. Postoperative recovery was uneventful, and the patient remained symptom-free during follow-up on infliximab therapy. This case highlights the importance of timely surgical intervention in complex CD and supports a multidisciplinary management approach.