Case report: A case of benign uterine leiomyoma with intense 18F-FDG uptake mimicking malignant tumor on PET/CT.

Uterine leiomyoma is a common benign tumor of the uterus and typically demonstrates low FDG uptake on 18F-FDG PET/CT. Intense FDG uptake in a uterine mass is generally considered suggestive of malignancy. Here, we report a case of uterine leiomyoma in a patient who presented with multiple areas of abnormal bone density throughout the body. To evaluate the possibility of bone metastases and to identify a potential primary tumor, 18F-FDG PET/CT was performed. Incidentally, a uterine mass with markedly increased FDG uptake was detected, raising strong suspicion of a uterine malignancy. However, postoperative histopathological examination ultimately confirmed the diagnosis of a benign uterine leiomyoma.