Future oncology (London, England) · 2019
Site-specific metastases of intrahepatic cholangiocarcinoma and its impact on survival: a population-based study.
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Yan Xia, Wang Peng, Zhu Zhengfeng, Ning Zhouyu, Xu Litao, Zhuang Liping, Sheng Jie, Meng Zhiqiang
Аннотация
Aim: Limited data exist on impact of the metastatic sites on survival in patients with metastatic intrahepatic cholangiocarcinoma (ICC). Methods: Patients with metastatic ICC were identified in the SEER from 2010 to 2015. Results: A total of 981 patients were identified, of this population, liver (57.9%) is the most common site of ICC metastases, followed by lung, bone and brain. Respective median overall survival and cancer-specific survival were 6 and 9 months in entire population. Further analysis suggested that patients treated by surgery to primary and/or metastatic lesions had a better survival outcome than patients had no surgery (p ≤ 0.001). Conclusion: Liver is the most common site for ICC metastases, local treatment such as surgery to primary or metastatic lesions obviously benefit patients.