Solid Pseudopapillary Neoplasm of Pancreas in a 26-Year-Old Female: A Case Report and Comprehensive Review of Literature.

Solid pseudopapillary neoplasm (SPN) is a rare, low-grade malignant tumor of the pancreas that predominantly affects young females. Although SPN is usually slow-growing and benign, it can exhibit local invasion or metastasis, emphasizing the need for prompt diagnosis and treatment. SPNs typically manifest as painless abdominal masses or are incidentally discovered on imaging. While most SPNs follow a benign course, they can invade nearby structures and, in rare instances, metastasize to the liver, omentum, or peritoneum. We report a rare case of a 26-year-old female who presented with a painless abdominal mass that had been growing for 8 years. Imaging revealed a heterogeneous pancreatic mass with signs of local invasion. The patient underwent distal pancreatectomy with en bloc splenectomy and segmental colectomy. This case highlights the importance of considering SPN in the differential diagnosis of abdominal masses in young females and emphasizes the role of surgical resection in achieving favorable outcomes, even in cases with extensive local spread.