Gan to kagaku ryoho. Cancer & chemotherapy · 2019
[Successful R0 Resection of Hilar Cholangiocarcinoma by Extrahepatic Bile Duct Resection Due to Accompanying Liver Dysfunction after Neoadjuvant Gemcitabine/Cisplatin/S-1 Combination Chemotherapy-A Case Report].
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Higashiguchi Masaya, Yamada Daisaku, Akita Hirofumi, Eguchi Hidetoshi, Iwagami Yoshifumi, Asaoka Tadafumi, Noda Takehiro, Gotoh Kunihito, Kobayashi Shogo, Sakai Daisuke, Hatano Etsuro, Ioka Tatsuya, Doki Yuichiro, Mori Masaki
Аннотация
A 79-year-old man was referred to our hospital for treatment of hilar cholangiocarcinoma with pathological evidence. FDG-PET/CT and EUS-FNA revealed regional lymph node metastasis and no distant metastasis before the treatment. He received 6 courses of neoadjuvant gemcitabine/cisplatin/S-1 combination chemotherapy, and the imaging studies revealed partial response. However, due to impairment of the liver after chemotherapy, it was difficult to perform subsequent major hepatectomy, and we decided to continue the chemotherapy. The impairment of the liver did not recover following 11 courses of chemotherapy; on the other hand, FDG uptake was diminished on FDG-PET, and cancer cells were not detected by repeated cytology and biopsy. Extrahepatic bile duct resection with dissection of regional lymph nodes was performed, and histopathological examinationof the resected specimensuggested R0 resection.