World journal of surgical oncology · 2025
Primary renal mucosa-associated lymphoid tissue lymphoma coexisting with immune thrombocytopenia.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
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He Jiatai, Deng Changqi, Huang Yu, Wang Miao, Wei Chengcheng, Xu Feixiang, Chen Ruokang, Wang Junduo, Yang Ming, Chen Zhaohui
Аннотация
BACKGROUND: Primary renal mucosa-associated lymphoid tissue (MALT) lymphoma is exceedingly rare. Although immune thrombocytopenia (ITP) may accompany lymphoproliferative disorders, its association with primary renal MALT lymphoma has not been previously reported.
CASE PRESENTATION: A 60-year-old male presenting with isolated thrombocytopenia was diagnosed with ITP during hematologic evaluation. Abdominal imaging incidentally revealed an 8.7 × 5.6 cm renal mass. Glucocorticoid therapy successfully stabilized platelet counts, enabling nephroureterectomy. Histopathological analysis demonstrated dense small lymphocyte infiltrates, with immunohistochemical confirmation of CD20 and Bcl-2 positivity establishing a diagnosis of MALT lymphoma. At six-month follow-up, the patient maintained disease-free status without adjuvant therapy.
CONCLUSIONS: We report a rare case of concurrent primary renal MALT lymphoma and ITP, achieving sustained remission through glucocorticoid therapy and surgical resection.
CASE PRESENTATION: A 60-year-old male presenting with isolated thrombocytopenia was diagnosed with ITP during hematologic evaluation. Abdominal imaging incidentally revealed an 8.7 × 5.6 cm renal mass. Glucocorticoid therapy successfully stabilized platelet counts, enabling nephroureterectomy. Histopathological analysis demonstrated dense small lymphocyte infiltrates, with immunohistochemical confirmation of CD20 and Bcl-2 positivity establishing a diagnosis of MALT lymphoma. At six-month follow-up, the patient maintained disease-free status without adjuvant therapy.
CONCLUSIONS: We report a rare case of concurrent primary renal MALT lymphoma and ITP, achieving sustained remission through glucocorticoid therapy and surgical resection.