The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2025
Five-view transabdominal with transvaginal ultrasound for diagnosis of congenital heart disease in high-risk fetuses during early pregnancy.
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Jiang Qiuxia, Shen Longyuan, Ruan Junxian, Huang Rongsen, Li Qiuwen, Du Yanyun, Liu Kunfa, Lyu Guorong
Аннотация
OBJECTIVES: This study aimed to evaluate the diagnostic value of five-view ultrasound for congenital heart disease (CHD) in high-risk fetuses aged 11-13 + 6 weeks.
METHODS: Pregnant patients underwent five-view echocardiography (upper abdominal transverse view, four-chamber view, three vessel-trachea view, ventricular outflow tract view, and bilateral subclavian artery view) at gestational age 11-13 + 6 weeks to assess its diagnostic efficacy for CHD during early pregnancy. The time required and image quality of the five-view echocardiographic scans were analyzed, and the results between trained and untrained attending sonographers were compared. Additionally, the diagnostic efficacies of the five-view and two-view methods (four-chamber view and three vessel-trachea view), as well as transabdominal and transabdominal with transvaginal ultrasound, were compared.
RESULTS: Trained sonographers required significantly less time to perform two-view and five-view echocardiography and achieved higher image quality scores, compared with untrained sonographers (all p < .05). The five-view method demonstrated sensitivity, specificity, positive predictive, negative predictive value, and area under the receiver operating characteristic curve values of 87.76%, 96.48%, 90.53%, 95.37%, and 0.921, respectively. These results indicated a superior diagnostic efficacy compared with the two-view method (p < .001). Furthermore, combined transabdominal and transvaginal ultrasound showed significantly higher diagnostic efficacy for cardiac malformations compared with transabdominal ultrasound alone (p < .001).
CONCLUSIONS: Five-view transabdominal combined with transvaginal ultrasound is an effective tool for diagnosing CHD in high-risk fetuses aged 11-13 + 6 weeks.
METHODS: Pregnant patients underwent five-view echocardiography (upper abdominal transverse view, four-chamber view, three vessel-trachea view, ventricular outflow tract view, and bilateral subclavian artery view) at gestational age 11-13 + 6 weeks to assess its diagnostic efficacy for CHD during early pregnancy. The time required and image quality of the five-view echocardiographic scans were analyzed, and the results between trained and untrained attending sonographers were compared. Additionally, the diagnostic efficacies of the five-view and two-view methods (four-chamber view and three vessel-trachea view), as well as transabdominal and transabdominal with transvaginal ultrasound, were compared.
RESULTS: Trained sonographers required significantly less time to perform two-view and five-view echocardiography and achieved higher image quality scores, compared with untrained sonographers (all p < .05). The five-view method demonstrated sensitivity, specificity, positive predictive, negative predictive value, and area under the receiver operating characteristic curve values of 87.76%, 96.48%, 90.53%, 95.37%, and 0.921, respectively. These results indicated a superior diagnostic efficacy compared with the two-view method (p < .001). Furthermore, combined transabdominal and transvaginal ultrasound showed significantly higher diagnostic efficacy for cardiac malformations compared with transabdominal ultrasound alone (p < .001).
CONCLUSIONS: Five-view transabdominal combined with transvaginal ultrasound is an effective tool for diagnosing CHD in high-risk fetuses aged 11-13 + 6 weeks.