Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego · 2005
[Salvage surgery after failure of radiotherapy in laryngeal cancer].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Lazecka Katarzyna, Osmólski Antoni, Osmólski Robert, Frenkiel Zofia, Wachulski Bartosz
Аннотация
OBJECTIVE: Efficacy of salvage surgery after radiotherapy failure in patients with laryngeal cancer.
MATERIAL AND METHODS: Retrospective analysis of 121 patients treated in our clinic between 1980 and 2003 (supraglottis--86 patients, glottis--35). In 70% of patients T-stage was T3 and T4 and regional metastases were present in 56% of cases. We performed statistical analysis of recurrence rates and 5-years survival according to Kaplan-Meier method.
RESULTS: Glottic localization (p = 0.02) and extracapsular spread (p = 0.03) were significant factors of final outcome. Local and regional stage was not significant factor of recurrence. Disease free 5-year survival was 53%.
CONCLUSION: Salvage surgery is a reasonable method that could save about 50% of patients after radiotherapy failure.
MATERIAL AND METHODS: Retrospective analysis of 121 patients treated in our clinic between 1980 and 2003 (supraglottis--86 patients, glottis--35). In 70% of patients T-stage was T3 and T4 and regional metastases were present in 56% of cases. We performed statistical analysis of recurrence rates and 5-years survival according to Kaplan-Meier method.
RESULTS: Glottic localization (p = 0.02) and extracapsular spread (p = 0.03) were significant factors of final outcome. Local and regional stage was not significant factor of recurrence. Disease free 5-year survival was 53%.
CONCLUSION: Salvage surgery is a reasonable method that could save about 50% of patients after radiotherapy failure.