Dento maxillo facial radiology · 2025
MR sialography and salivary gland SPECT/CT for parotid glands in patients with Sjögren's syndrome.
СтатьяНазвание и аннотация: Перевод в очереди
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Shirai Ai, Nakatani Yuya, Toya Shuji, Ogura Ichiro
Аннотация
OBJECTIVE: The aim of this study was to investigate MR sialography and SPECT/CT for parotid glands in Sjögren's syndrome patients.
METHODS: Thirty Sjögren's syndrome patients underwent MR sialography and SPECT/CT. The MR sialographic stagings of Sjögren's syndrome were determined by the criteria (stage 0: normal; stage 1: punctate appearance; stage 2: globular appearance; stage 3: cavitary appearance; stage 4: destructive appearance). The maximum standardized uptake value (SUVmax) of the right and left parotid glands with SPECT/CT was obtained using a workstation and software. MR sialographic stagings and SUVmax of parotid glands were evaluated at pre- and post-stimulation and ratio of pre- to post-stimulation.
RESULTS: Regarding pre-stimulation, the SUVmax of stage 0 (31.9 ± 19.3) was significantly higher than that of stage 2 (19.7 ± 7.5, P = .046), stage 3 (10.2 ± 7.1, P < .001) and stage 4 (6.8 ± 4.3, P < .001). Furthermore, the SUVmax at ratio of pre- to post-stimulation of stage 0 (1.87 ± 0.55) was significantly higher than that of stage 3 (1.16 ± 0.30, P = .001) and stage 4 (1.16 ± 0.40, P < .001).
CONCLUSION: This study suggests that MR sialography and SPECT/CT SUV are effective tool for the management of Sjögren's syndrome patients.
METHODS: Thirty Sjögren's syndrome patients underwent MR sialography and SPECT/CT. The MR sialographic stagings of Sjögren's syndrome were determined by the criteria (stage 0: normal; stage 1: punctate appearance; stage 2: globular appearance; stage 3: cavitary appearance; stage 4: destructive appearance). The maximum standardized uptake value (SUVmax) of the right and left parotid glands with SPECT/CT was obtained using a workstation and software. MR sialographic stagings and SUVmax of parotid glands were evaluated at pre- and post-stimulation and ratio of pre- to post-stimulation.
RESULTS: Regarding pre-stimulation, the SUVmax of stage 0 (31.9 ± 19.3) was significantly higher than that of stage 2 (19.7 ± 7.5, P = .046), stage 3 (10.2 ± 7.1, P < .001) and stage 4 (6.8 ± 4.3, P < .001). Furthermore, the SUVmax at ratio of pre- to post-stimulation of stage 0 (1.87 ± 0.55) was significantly higher than that of stage 3 (1.16 ± 0.30, P = .001) and stage 4 (1.16 ± 0.40, P < .001).
CONCLUSION: This study suggests that MR sialography and SPECT/CT SUV are effective tool for the management of Sjögren's syndrome patients.