Journal of veterinary internal medicine · 2025
In Vivo Radiographic Characteristics Associated With the Mineral Composition of Calcium Oxalate, Struvite, and Cystine Lower Urinary Tract Uroliths in Dogs.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Pulido Vega Diego, Motteau-Lévêque Mathieu, Maurey Christelle, Mortier Jeremy
Аннотация
BACKGROUND: Identifying urolith mineral composition (UMC) is crucial for treatment and prevention; however, current data rely on macroscopic or ex vivo studies.
OBJECTIVES: To describe in vivo radiographic characteristics of canine lower urinary tract (LUT) uroliths and identify discriminating radiographic features among UMC types.
ANIMALS: Two hundred and two dogs with LUT uroliths composed of ≥ 70% calcium oxalate (n = 109), struvite (n = 58), or cystine (n = 35).
METHODS: Retrospective cross-sectional study. Radiographs were evaluated for urolith size, shape, surface, borders, internal architecture, and quantitative radiopacity, and also assessed using a ratio of urolith-to-L5 vertebra pixel values (UOR). The diagnostic performance of urolith size and UOR was assessed with receiver operating characteristics (ROC) curves, calculating the area under the ROC curve (AUC).
RESULTS: Calcium oxalate uroliths were often highly radiopaque, associated with concurrent nephroliths, had unique shapes such as bosselated or spiculated, and less commonly ovoid. Struvite uroliths were larger (median: 15 mm; IQR: 8.1-25.8 mm) with a cut-off of ≥ 11 mm (AUC = 0.82, p < 0.001; specificity: 91%, sensitivity: 67%) and were associated with pyramidal shapes or solitary cystoliths. Cystine uroliths had lower radiopacity (median UOR: 0.71; IQR: 0.63-0.80), with a cut-off of UOR ≤ 0.83 (AUC = 0.81, p < 0.001; specificity: 67%, sensitivity: 84%).
CONCLUSIONS AND CLINICAL IMPORTANCE: In vivo radiographic characteristics such as size, shape, and radiopacity can help differentiate LUT mineral compositions, enabling non-invasive diagnosis and guiding treatment.
OBJECTIVES: To describe in vivo radiographic characteristics of canine lower urinary tract (LUT) uroliths and identify discriminating radiographic features among UMC types.
ANIMALS: Two hundred and two dogs with LUT uroliths composed of ≥ 70% calcium oxalate (n = 109), struvite (n = 58), or cystine (n = 35).
METHODS: Retrospective cross-sectional study. Radiographs were evaluated for urolith size, shape, surface, borders, internal architecture, and quantitative radiopacity, and also assessed using a ratio of urolith-to-L5 vertebra pixel values (UOR). The diagnostic performance of urolith size and UOR was assessed with receiver operating characteristics (ROC) curves, calculating the area under the ROC curve (AUC).
RESULTS: Calcium oxalate uroliths were often highly radiopaque, associated with concurrent nephroliths, had unique shapes such as bosselated or spiculated, and less commonly ovoid. Struvite uroliths were larger (median: 15 mm; IQR: 8.1-25.8 mm) with a cut-off of ≥ 11 mm (AUC = 0.82, p < 0.001; specificity: 91%, sensitivity: 67%) and were associated with pyramidal shapes or solitary cystoliths. Cystine uroliths had lower radiopacity (median UOR: 0.71; IQR: 0.63-0.80), with a cut-off of UOR ≤ 0.83 (AUC = 0.81, p < 0.001; specificity: 67%, sensitivity: 84%).
CONCLUSIONS AND CLINICAL IMPORTANCE: In vivo radiographic characteristics such as size, shape, and radiopacity can help differentiate LUT mineral compositions, enabling non-invasive diagnosis and guiding treatment.