Respiratory medicine · 2025
Nasopharyngeal airway relieves upper airway obstruction to alleviate hypoxemia during painless gastrointestinal endoscopy for obese outpatients: a prospective randomized controlled trial.
СтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Peng Yanhua, Deng Lei, Dai Shiyu, Xiang Dongmei, Zhou Rui, Zhang Xianjie, Tian Lei, Zhou Yukai, Chen Wenya, Zhou Jun
Аннотация
PURPOSES: To investigate the efficacy of nasopharyngeal airway intubation in alleviating hypoxemia in obese outpatients undergoing painless gastrointestinal endoscopy.
METHODS: This prospective single-center randomized controlled trial was conducted at the Deyang People's Hospital, Deyang, China. Obese outpatients scheduled for painless gastrointestinal endoscopy were randomly assigned to either the nasopharyngeal airway (Group N) or control group (Group C). Nasopharyngeal airway intubation was performed prior to the examination. The primary outcome was the incidence of hypoxemia, while secondary outcomes included intubation duration, procedural interruptions due to desaturation, security events, visual analog scale (VAS) scores, satisfaction scores, and device placement metrics.
RESULTS: A total of 88 patients in Group N and 86 patients in Group C were analyzed. The incidence of hypoxemia was 2.27 % in Group N compared to 37.21 % in Group C (P < 0.001). Post-endoscopy, pulse oxygen saturation in Group C was significantly lower than in Group N (P = 0.001). Vital signs showed no differences at the time of intubation and extubation (P > 0.05). Satisfaction scores for endoscopists and anesthesiologists were higher in Group N than in Group C, with scores of 9.97 ± 0.18 vs. 9.73 ± 0.82 (P = 0.01) and 9.89 ± 0.47 vs. 9.10 ± 1.15 (P < 0.001), respectively. In Group N, 87 patients received nasopharyngeal airway intubation, with 69 intubations completed within 5 s, 18 within 10 s, and one patient requiring two attempts within 15 s. In Group N, the VAS score for all patients was ≤3.
CONCLUSIONS: Prophylactic nasopharyngeal airway intubation effectively alleviates hypoxemia in obese outpatients undergoing painless gastrointestinal endoscopy without increasing side effects. This cost-effective intervention offers a superior strategy for managing hypoxemia in this patient population.
METHODS: This prospective single-center randomized controlled trial was conducted at the Deyang People's Hospital, Deyang, China. Obese outpatients scheduled for painless gastrointestinal endoscopy were randomly assigned to either the nasopharyngeal airway (Group N) or control group (Group C). Nasopharyngeal airway intubation was performed prior to the examination. The primary outcome was the incidence of hypoxemia, while secondary outcomes included intubation duration, procedural interruptions due to desaturation, security events, visual analog scale (VAS) scores, satisfaction scores, and device placement metrics.
RESULTS: A total of 88 patients in Group N and 86 patients in Group C were analyzed. The incidence of hypoxemia was 2.27 % in Group N compared to 37.21 % in Group C (P < 0.001). Post-endoscopy, pulse oxygen saturation in Group C was significantly lower than in Group N (P = 0.001). Vital signs showed no differences at the time of intubation and extubation (P > 0.05). Satisfaction scores for endoscopists and anesthesiologists were higher in Group N than in Group C, with scores of 9.97 ± 0.18 vs. 9.73 ± 0.82 (P = 0.01) and 9.89 ± 0.47 vs. 9.10 ± 1.15 (P < 0.001), respectively. In Group N, 87 patients received nasopharyngeal airway intubation, with 69 intubations completed within 5 s, 18 within 10 s, and one patient requiring two attempts within 15 s. In Group N, the VAS score for all patients was ≤3.
CONCLUSIONS: Prophylactic nasopharyngeal airway intubation effectively alleviates hypoxemia in obese outpatients undergoing painless gastrointestinal endoscopy without increasing side effects. This cost-effective intervention offers a superior strategy for managing hypoxemia in this patient population.