Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology · 2001
[Prognostic significance of CD57+ cell level and pTNM staying system in patients with laryngeal cancer].
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Zheng M, Luan X
Аннотация
OBJECTIVE: To analyze the prognostic value of the pTNM clinical staying system, as well as the CD57+ cells level in peripheral blood samples of the patients with laryngeal carcinoma.
METHOD: The CD57+ cells level of peripheral blood was determined with SAP method in 34 patients with laryngeal carcinoma and 16 normal subjects. The pTNM clinical stage was T1-2 in 13, T3-4 in 21; pN+ in 10, pN0 in 24; supraglottis in 8, glottis in 23; hypoglottis in 3; pathologic differentiation G1 in 11, G2,3 in 23.
RESULT: The CD57+ cells level significantly increased (pN+ vs. pNo). In the 12nd month actual survival were significantly different (T1,2 vs. T3,4, pN0 vs. pN+, G1 vs G2,3, supraglottis vs. glottis and hypoglottis, CD57+ > or = 15% vs. CD57+ < 15%). In the 24th month and 36th month actual survival were significantly different (pN0 vs. pN+, G1 vs G2,3, supraglottis. glottis and hypoglottis, CD57+ > or = 15% vs. CD57+ < 15%). In the 48th month actual survival were significantly different only (pN0 vs. pN+, supraglottis vs. glottis and hypo glottis, CD57+ > or = 15% vs. CD57+ < 15%).
CONCLUSION: These results suggested that the assessment of pTNM system and the CD57+ cells level have significance for prognosis of patients with laryngeal carcinoma.
METHOD: The CD57+ cells level of peripheral blood was determined with SAP method in 34 patients with laryngeal carcinoma and 16 normal subjects. The pTNM clinical stage was T1-2 in 13, T3-4 in 21; pN+ in 10, pN0 in 24; supraglottis in 8, glottis in 23; hypoglottis in 3; pathologic differentiation G1 in 11, G2,3 in 23.
RESULT: The CD57+ cells level significantly increased (pN+ vs. pNo). In the 12nd month actual survival were significantly different (T1,2 vs. T3,4, pN0 vs. pN+, G1 vs G2,3, supraglottis vs. glottis and hypoglottis, CD57+ > or = 15% vs. CD57+ < 15%). In the 24th month and 36th month actual survival were significantly different (pN0 vs. pN+, G1 vs G2,3, supraglottis. glottis and hypoglottis, CD57+ > or = 15% vs. CD57+ < 15%). In the 48th month actual survival were significantly different only (pN0 vs. pN+, supraglottis vs. glottis and hypo glottis, CD57+ > or = 15% vs. CD57+ < 15%).
CONCLUSION: These results suggested that the assessment of pTNM system and the CD57+ cells level have significance for prognosis of patients with laryngeal carcinoma.