Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2009
Primary myelodysplastic syndrome in Jordan: a single-centre experience.
СтатьяНазвание и аннотация: Перевод в очереди
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Awidi Abdalla, Magableh Ahmad, Taimeh Ziad, Ayyad Hashim, Bsoul Nazzal, Tarawneh Musleh
Аннотация
OBJECTIVE: Study of the disease patterns and clinical evaluation of myelodysplastic syndrome (MDS).
SUBJECTS AND METHODS: A retrospective analysis was carried out on 85 patients, with MDS who were followed up over a period of 23 years at Jordan University Hospital, Amman, Jordan. Cases were analyzed according to the French, American and British Classification.
RESULTS: Of the 85 patients, 42 (49.4%) were females and 43 (50%) males; mean age was 59 +/- 19 years (range 18-88). Most subtypes found in patients were refractory anemia (RA) in 27 (31.8%) and RA with excess blasts (RAEB) in 28 (32.9%). Adverse prognostic indicators were RAEB subtype and requirement for blood transfusion.
CONCLUSION: Our findings showed that MDSs appeared at a younger age and tended to be of the aggressive subtype. Chronic myelomonocytic leukemia subtype seemed to appear dominantly in men.
SUBJECTS AND METHODS: A retrospective analysis was carried out on 85 patients, with MDS who were followed up over a period of 23 years at Jordan University Hospital, Amman, Jordan. Cases were analyzed according to the French, American and British Classification.
RESULTS: Of the 85 patients, 42 (49.4%) were females and 43 (50%) males; mean age was 59 +/- 19 years (range 18-88). Most subtypes found in patients were refractory anemia (RA) in 27 (31.8%) and RA with excess blasts (RAEB) in 28 (32.9%). Adverse prognostic indicators were RAEB subtype and requirement for blood transfusion.
CONCLUSION: Our findings showed that MDSs appeared at a younger age and tended to be of the aggressive subtype. Chronic myelomonocytic leukemia subtype seemed to appear dominantly in men.
Предметные рубрики MeSH
AdolescentAdultAge DistributionAgedAged, 80 and overAnemia, Refractory, with Excess of BlastsAnemia, SideroblasticDeveloping CountriesDisease ProgressionFemaleHospitals, UniversityHumansJordanKaplan-Meier EstimateLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMaleMiddle AgedRetrospective StudiesSex DistributionYoung Adult